Reverse Engineering Time Discrete Finite Dynamical Systems: A Feasible Undertaking?
نویسندگان
چکیده
منابع مشابه
Reverse Engineering Time Discrete Finite Dynamical Systems: A Feasible Undertaking?
With the advent of high-throughput profiling methods, interest in reverse engineering the structure and dynamics of biochemical networks is high. Recently an algorithm for reverse engineering of biochemical networks was developed by Laubenbacher and Stigler. It is a top-down approach using time discrete dynamical systems. One of its key steps includes the choice of a term order, a technicality ...
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Recently a new algorithm for reverse engineering of biochemical networks was developed by Laubenbacher and Stigler. It is based on methods from computational algebra and finds most parsimonious models for a given data set. We derive mathematically rigorous estimates for the expected amount of data needed by this algorithm to find the correct model. In particular, we demonstrate that for one typ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2009
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0004939